See your doctor if you have any of these symptoms. However, people with very high blood pressure may have headaches, blurred or double vision, regular nosebleeds, difficulty breathing, chest pain, irregular heartbeat, blood in the urine, confusion, or pounding in the chest, neck, or ears. High blood pressure does not usually cause symptoms. High blood pressure is also a major risk factor for heart failure, atrial fibrillation, chronic kidney disease, peripheral artery disease, and cognitive decline. High blood pressure is the leading global cause of premature death, accounting for almost ten million deaths in 2015, of which 4.9 million were due to ischaemic heart disease and 3.5 million were due to stroke. Around 30–45% of adults are affected, rising to more than 60% of people over 60 years of age. More than one billion people have hypertension (high blood pressure) worldwide. These pills are already available and should massively improve the success of treatment, with corresponding reductions in strokes, heart disease, and early deaths.” Professor Bryan Williams, ESC Chairperson of the Guidelines Task Force, University College London, UK, said: “The vast majority of patients with high blood pressure should start treatment with two drugs as a single pill. Non-adherence increases with the number of pills, so administering the two drugs (or three if needed) in a single tablet “could transform blood pressure control rates”, state the guidelines. It is now recognised that a major reason for poor rates of blood pressure control is that patients do not take their pills. At least 80% of patients should have been upgraded to two drugs, yet most remained on one drug. This suffered from “physician inertia”, in which doctors were reluctant to change the initial strategy despite its lack of success. The previous recommendation was for step-wise treatment, which meant starting with one drug then adding a second and third if needed. The guidelines recommend starting most patients on two blood pressure lowering drugs, not one. It is available as a prescription only medicine and is commonly used for Acute Lymphocytic Leukemia, Adrenocortical Insufficiency, Adrenogenital Syndrome, Allergic Reactions, Allergic Rhinitis, Ankylosing Spondylitis, Aspiration Pneumonia, Asthma, Atopic Dermatitis, Autoimmune Hemolytic Anemia, Berylliosis, Bullous Pemphigoid, Bursitis, Chorioretinitis, Cluster Headaches, Cogan's Syndrome, Conjunctivitis, Allergic, COPD, Corneal Ulcer, Crohn's Disease, Acute, Dermatitis Herpetiformis, Dermatomyositis, Diffuse Large B-Cell Lymphoma, Eczema, Epicondylitis, Tennis Elbow, Erythroblastopenia, Fibromyalgia, Giant Cell Arteritis, Gouty Arthritis, Graft-versus-host disease, Herpes Zoster, Herpes Zoster Iridocyclitis, Hypercalcemia of Malignancy, Idiopathic Thrombocytopenic Purpura, Immunosuppression, Inflammatory Bowel Disease, Inflammatory Conditions, Interstitial Lung Disease, Iridocyclitis, Iritis, Juvenile Rheumatoid Arthritis, Keratitis, Leukemia, Lichen Planus, Lichen Sclerosus, Loeffler's Syndrome, Lymphoma, Mixed Connective Tissue Disease, Multiple Sclerosis, Mycosis Fungoides, Nephrotic Syndrome, Neurosarcoidosis, Osteoarthritis, Pemphigoid, Pemphigus, Pharyngitis, Polymyalgia Rheumatica, Polymyositis/Dermatomyositis, Psoriasis, Psoriatic Arthritis, Ramsay Hunt Syndrome, Rheumatoid Arthritis, Sarcoidosis, Scleroderma, Seborrheic Dermatitis, Sinusitis, Skin Rash, Synovitis, Systemic Lupus Erythematosus, Systemic Sclerosis, Thrombocytopenia, Toxic Epidermal Necrolysis, Tuberculosis, Extrapulmonary, Tuberculous Meningitis, Ulcerative Colitis, Active, Uveitis, Posterior, Lupus Nephritis, Lichen Planopilaris, Optic Neuritis.Munich, Germany – : A single pill with two drugs could transform blood pressure treatment, according to the 2018 European Society of Cardiology (ESC) and European Society of Hypertension (ESH) Guidelines on arterial hypertension published online today in European Heart Journal (1), and on the ESC website.
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